Search on: CONJUGATE VACCINES 
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Descriptor English:   Vaccines, Conjugate 
Descriptor Spanish:   Vacunas Conjugadas 
Descriptor Portuguese:   Vacinas Conjugadas 
Synonyms English:   Conjugate Vaccines  
Tree Number:   D20.215.894.865.900
D23.050.865.900
Definition English:   Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection. 
Indexing Annotation English:   "induce antibody formation in people not responsive to polysaccharide alone"; semisynthetic vaccines; coord NIM with specific vaccine (IM)
History Note English:   94 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
CT contraindications DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
MI microbiology PD pharmacology
PO poisoning RE radiation effects
ST standards TU therapeutic use
TO toxicity UL ultrastructure
UR urine VI virology
Record Number:   30984 
Unique Identifier:   D018074 

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